References for May 2026
Five facts about physiotherapy and anterior cruciate ligament reconstruction
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- Zbrojkiewicz, D., Vertullo, C. and Grayson, J.E. (2018). Increasing rates of anterior cruciate ligament reconstruction in young Australians, 2000–2015. Medical Journal of Australia, 208: 354-358. https://doi.org/10.5694/mja17.00974
- Maniar, N., et al. (2022). Trends in Australian knee injury rates: An epidemiological analysis of 228,344 injuries over 20 years. The Lancet Regional Health – Western Pacific, 21(100409). https://doi.org/10.1016/j.lanwpc.2022.100024
- Ardern CL, et al. (2018). 2018 International Olympic Committee consensus statement on prevention, diagnosis and management of paediatric anterior cruciate ligament (ACL) injuries. British Journal of Sports Medicine 2018;52:422-438. https://doi.org/10.1136/bjsports-2018-099060
- Kan, A., English, T., Penny, A., Franc-Smith, J., Tudor, F., & Sattler, L. (2025). Does the addition of a lateral extra-articular procedure to a primary anterior cruciate ligament reconstruction result in superior functional and clinical outcomes? A systematic review and meta-analysis of randomized controlled trials. The American Journal of Sports Medicine, 53(11), 2749-2760.
- Beckers, L., Vivacqua, T., Firth, A. D., & Getgood, A. M. (2021). Clinical outcomes of contemporary lateral augmentation techniques in primary ACL reconstruction: a systematic review and meta-analysis. Journal of Experimental Orthopaedics, 8(1), 59.
- Onggo, J. R., Rasaratnam, H. K., Nambiar, M., Onggo, J. D., Pai, V., Damasena, I., ... & Babazadeh, S. (2022). Anterior cruciate ligament reconstruction alone versus with lateral extra-articular tenodesis with minimum 2-year follow-up: A meta-analysis and systematic review of randomized controlled trials. The American Journal of Sports Medicine, 50(4), 1137-1145.
- Kunze, K. N., Manzi, J., Richardson, M., White, A. E., Coladonato, C., DePhillipo, N. N., ... & Chahla, J. (2021). Combined anterolateral and anterior cruciate ligament reconstruction improves pivot shift compared with isolated anterior cruciate ligament reconstruction: a systematic review and meta-analysis of randomized controlled trials. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 37(8), 2677-2703.
- Grindem, H., et al. (2016). "Simple decision rules can reduce reinjury risk by 84% after ACL reconstruction." BJSM.
- White T, Castro M, Antonio L, Hing W, Tudor F, Sattler L. Quadriceps, hamstring and patella tendon autografts for primary anterior cruciate ligament reconstruction demonstrate similar clinical outcomes, including graft failure, joint laxity and complications: a systematic review with meta-analysis of randomised controlled trials. Knee Surg Sports Traumatol Arthrosc. 2025;1–16.
- Dai W, Leng X, Wang J, Cheng J, Hu X, Ao Y. Quadriceps tendon autograft versus bone-patellar tendon-bone and hamstring tendon autografts for anterior cruciate ligament reconstruction: a systematic review and meta-analysis. Am J Sports Med. 2022;50(12):3425–39.
- Tuca M, Valderrama I, Eriksson K, Tapasvi S. Current trends in anterior cruciate ligament surgery: a worldwide benchmark study. J ISAKOS. 2023;8(1):2–10.
- Ardern, C. L., Taylor, N. F., Feller, J. A., & Webster, K. E. (2014). Fifty-five percent return to competitive sport following ACL reconstruction surgery: An updated systematic review and meta-analysis. British Journal of Sports Medicine, 48(21), 1543–1552.
- Ardern, C. L., Taylor, N. F., Feller, J. A., Whitehead, T. S., & Webster, K. E. (2013). Psychological responses matter in returning to pre-injury level of sport after ACL reconstruction surgery. American Journal of Sports Medicine, 41(7), 1549–1558.
- Webster, K. E., Feller, J. A., & Lambros, C. (2008). Development and preliminary validation of a scale to measure the psychological impact of returning to sport following anterior cruciate ligament reconstruction surgery. Physical Therapy in Sport, 9(1), 9–15.
Common myths about hypermobility and EDS
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- Hakim, A.T., Brad; Fancomano, Claire, A framework for the classification of joint hypermobility and related conditions. American journal of medical genetics. Part C, Seminars in medical genetics, 2017.
- Hakim, A., Hypermobile Ehlers-Danlos Syndrome Synonyms: Ehlers-Danlos Syndrome Hypermobility Type, Ehlers-Danlos Syndrome Type III, hEDS. October 22 ed. GeneReviews®, ed. F.J. Adam MP, Mirzaa GM, et al., . 2024, University of Washington, Seattle: U.S. National Library of Medicine. 16.
- Francomano, A.C., et al., Introduction: An overview of the Ehlers-Danlos syndromes and hypermobility spectrum disorders, in The Symptom-Based Handbook for Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders. 2024. p. 1-17.
- Wang, T.J., et al., Fascial Pathophysiology in Hypermobility Spectrum Disorders and Hypermobile Ehlers–Danlos Syndrome: A Review of Emerging Evidence, in Int J Mol Sci. 2025, MDPI AG: Switzerland. p. 5587.
- Victoria Daylor, M.G., Amy Weintraub, Rebecca Byrd, Taylor Petrucci, Matthew Huff, Kathryn Byerly, Roman Fenner, Sydney Severance, Charlotte Griggs, Amol Sharma, Paldeep Atwal, Steven A. Kautz, Steven Shapiro, Kimberly Youkhana, Mark Lavallee, Allison Wilkerson, Michelle Nichols, Alan Snyder, Josef Eichinger, Sunil Patel, Anne Maitland, Cortney Gensemer, View ORCID ProfileRussell A. Norris, Defining the Clinical Complexity of hEDS and HSD: A Global Survey of Diagnostic Challenge, Comorbidities, and Unmet Needs. 2024.
- Gensemer, C., et al., Hypermobile Ehlers‐Danlos syndromes: Complex phenotypes, challenging diagnoses, and poorly understood causes. Developmental dynamics, 2021. 250(3): p. 318-344.
- Petrucci, T., et al., Phenotypic Clusters and Multimorbidity in Hypermobile Ehlers-Danlos Syndrome. Mayo Clinic proceedings. Innovations, quality & outcomes, 2024. 8(3): p. 253-262.
- Nicholson, L.L., et al., Hypermobility syndromes in children and adolescents: Assessment, diagnosis and multidisciplinary management. Australian journal of general practice, 2022. 51(6): p. 409-414.
- Demmler, J.C., et al., Diagnosed prevalence of Ehlers-Danlos syndrome and hypermobility spectrum disorder in Wales, UK: a national electronic cohort study and case–control comparison. BMJ open, 2019. 9(11): p. e031365-e031365.
- Society, T.E.-D. Prevalence of Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorders (HSD). 2023 2025 August 20, 2024]; Available from: https://www.ehlers-danlos.com/prevalence/.
- Blajwajs, L., et al., Hypermobility prevalence, measurements, and outcomes in childhood, adolescence, and emerging adulthood: a systematic review. Rheumatology international, 2023. 43(8): p. 1423-1444.
- Singh, H., et al., Beighton scores and cut-offs across the lifespan: cross-sectional study of an Australian population. Rheumatology (Oxford, England), 2017. 56(11): p. 1857-1864.
- Halverson, C.M.E., et al., Comorbidity, misdiagnoses, and the diagnostic odyssey in patients with hypermobile Ehlers-Danlos syndrome. Genetics in Medicine Open, 2023. 1(1): p. 100812.
- Trudgian, R. and T. Flood, An exploration of the journey to diagnosis of Ehlers-Danlos Syndrome (EDS) for women living in Australia. PloS one, 2024. 19(7): p. e0307574.
- Hakim, A., R. Keer, and R. Grahame, Hypermobility, fibromyalgia, and chronic pain. 2010, Edinburgh: Churchill Livingstone Elsevier.
- Hermanns-Lê, T., G.E. Piérard, and P. Angenot, Fibromyalgia: an unrecognized Ehlers-Danlos syndrome hypermobile type? Revue médicale de Liège, 2013. 68(1): p. 22-24.
- Voermans, N.C., et al., Pain in Ehlers-Danlos Syndrome Is Common, Severe, and Associated with Functional Impairment. Journal of pain and symptom management, 2010. 40(3): p. 370-378.
- Börsch, N., et al., Treating pain in patients with Ehlers–Danlos syndrome: Multidisciplinary management of a multisystemic disease. Schmerz (Berlin, Germany), 2024. 38(1): p. 12-18.
- Kumar, B.M.D. and P.M.D.P. Lenert, Joint Hypermobility Syndrome: Recognizing a Commonly Overlooked Cause of Chronic Pain. The American journal of medicine, 2017. 130(6): p. 640-647.
- Molander, P., et al., Interdisciplinary pain rehabilitation for patients with Ehlers-Danlos syndrome and hypermobility spectrum disorders. Journal of rehabilitation medicine, 2024. 56: p. jrm12431-jrm12431.
- Pepe, A., et al., 39. Central sensitization as the mechanism underlying pain in joint hypermobility syndrome/Ehlers–Danlos syndrome, hypermobility type. Clinical neurophysiology, 2016. 127(12): p. e332-e332.
- Scheper, M.C., et al., Chronic pain in hypermobility syndrome and Ehlers-Danlos syndrome (hypermobility type): it is a challenge Chronic pain in hypermobility syndrome and Ehlers-Danlos syndrome (hypermobility type): it is a challenge. Journal of pain research, 2015. 2015(default): p. 591-601.
- Vlaeyen, J.W.S. and S.J. Linton, Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art, in Pain. 2000, Elsevier B.V: Amsterdam. p. 317-332.
- Rombaut, L., et al., Chronic pain in patients with the hypermobility type of Ehlers–Danlos syndrome: evidence for generalized hyperalgesia. Clinical rheumatology, 2015. 34(6): p. 1121-1129.
- Coussens, M., et al., Muscle Strength, Muscle Mass and Physical Impairment in Women with hypermobile Ehlers-Danlos syndrome and Hypermobility Spectrum Disorder. Journal of musculoskeletal & neuronal interactions, 2022. 22(1): p. 5-14.
- Smith, Andrew C., et al., Leg Muscle Volume, Intramuscular Fat and Force Generation: Insights From a Computer‐Vision Model and Fat‐Water MRI. Journal of cachexia, sarcopenia and muscle, 2025. 16(1): p. e13735-n/a.
- Wang, L., T.G. Valencak, and T. Shan, Fat infiltration in skeletal muscle: Influential triggers and regulatory mechanism. iScience, 2024. 27(3): p. 109221.
- Murray, G.M. and B.J. Sessle, Pain-sensorimotor interactions: New perspectives and a new model. Neurobiology of pain, 2024. 15: p. 100150-100150.
- Broida, S.E., et al., Management of shoulder instability in hypermobility-type Ehlers-Danlos syndrome. JSES reviews, reports, and techniques, 2021. 1(3): p. 155-164.
- Buryk-Iggers, S., et al., Exercise and Rehabilitation in People With Ehlers-Danlos Syndrome: A Systematic Review. Archives of rehabilitation research and clinical translation, 2022. 4(2): p. 100189-100189.
- Russek, L.N., P. Stott, and J. Simmonds, Recognizing and Effectively Managing Hypermobility-Related Conditions. Physical therapy, 2019. 99(9): p. 1189-1200.
- Lau, D.H., et al., Postural Orthostatic Tachycardia Syndrome: A State-of-the-Art Review. HEART LUNG AND CIRCULATION, 2026. 35(2): p. 171-185.
- Fu, Q. and B.D. Levine, Exercise and non-pharmacological treatment of POTS. Autonomic neuroscience, 2018. 215: p. 20-27.
- Cortez, M.M., et al., Impact of exercise to treat postural orthostatic tachycardia syndrome: a systematic review. Frontiers in neurology, 2025. 16: p. 1567708.
- Slater P., et al., Impact of HSD/hEDS With Co-existent Postural Orthostatic Tachycardia Syndrome on QoL, Mental Health and Pain, in 2022 International Scientific Symposium on the Ehlers-Danlos Syndromes and Hyper mobility Spectrum Disorders. 2022, Ehlers-Danlos Syndrome Society: Rome. p. 197 -198.
- Daylor, V., et al., Defining the Clinical Complexity of hEDS and HSD: A Global Survey of Diagnostic Challenge, Comorbidities, and Unmet Needs. 2025.
- Engelbert, R.H.H., et al., The evidence‐based rationale for physical therapy treatment of children, adolescents, and adults diagnosed with joint hypermobility syndrome/hypermobile Ehlers Danlos syndrome. American journal of medical genetics. Part C, Seminars in medical genetics, 2017. 175(1): p. 158-167.
- Garreth Brittain, M., et al., Physical therapy interventions in generalized hypermobility spectrum disorder and hypermobile Ehlers-Danlos syndrome: a scoping review. Disability and rehabilitation, 2024: p. 1-18.
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