1. ICU survivors and their families face ongoing challenges

As critical care medicine advances, it is increasingly likely that a patient will survive a critical illness in the ICU (Herridge & Azoulay 2023). 

These advances in life-saving treatment have also created an iatrogenic state in which the manifestations of surviving critical illness are often the consequence of medical treatments rather than the initial pathology (Bemis-Dougherty & Smith 2013). 

There is growing awareness of the long-term effects of emerging from a critical illness with ongoing disability (Herridge & Azoulay 2023) and a recognition that many patients live with post–intensive care syndrome (PICS) (Needham et al 2012). 

PICS is characterised by a combination of new or worsening cognitive (Pandharipande et al 2013, Iwashyna et al 2010), functional (Herridge et al 2011) and psychological (Wade et al 2012) issues that persist following hospital discharge. 

Family members also encounter psychological challenges, known as post–intensive care syndrome-family or PICS-F (Davidson et al 2012). 

Emerging evidence in the literature shows that awareness of PICS and PICS-F is limited among many hospitalists and healthcare practitioners and that its management is poorly understood (Kahn et al 2007). 

Physiotherapists practising outside the ICU should be aware of the consequences of PICS so that ICU survivors in hospitals, rehabilitation centres and outpatient clinics with deterioration of physical, cognitive and mental abilities are diagnosed early and accurately and receive appropriate services (Needham et al 2012).

2. Symptoms of PICS include muscle loss, weakness and higher mortality

Despite what we try to do in the ICU with early mobilisation and liberating patients from ventilation, ICU-acquired weakness is prevalent among ICU survivors (Denehy et al 2017). 

Common physical symptoms include critical illness myopathy, joint stiffness and fatigue. 

Muscle wasting occurs early and rapidly during the first week of critical illness and is more severe in those with multiple organ failure (Puthucheary et al 2013). 

Patients can lose up to 40 per cent of their muscle mass during an ICU stay, with potentially significant effects on their long-term function and physical capacity (Griffiths & Jones 1999). Rebuilding this much muscle can take over a year (Griffiths & Jones 1999). Patients may have difficulty with activities such as climbing stairs, getting out of the bath, turning off taps, driving a car or returning to work. This can then contribute to a fear of falling and increase their chance of hospital readmission (Griffiths & Jones 1999). ICU-acquired weakness has been associated with higher one-year mortality (Hermans et al 2014) and skeletal muscle weakness at discharge was independently associated with worse five-year survival (Dinglas et al 2017). This finding was consistent regardless of whether muscle weakness persisted or resolved in the post-ICU period.

3. Immobility in the ICU is harmful

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Immobility is common in the ICU and is largely due to sedation practices, which are often essential when patients are critically unwell. One way of managing this is to encourage early mobilisation, which has been shown to be safe and feasible (Stiller 2013). However, there is still conflicting evidence when it comes to dose, duration and timing. Along with the detrimental effects of muscle wasting, other factors contribute to poorer outcomes for our patients due to immobility and the sequelae of an ICU admission. Labeau et al (2021) reported in an international point prevalence study that ICU- acquired pressure injuries are common and that those who develop them have poorer outcomes, making it all the more important that our patients are regularly mobilised.
Another issue is that patients with challenging behaviours in the ICU are often physically restrained. Nursing and allied health involvement is likely to be effective in reducing rates of physical restraint (Franks et al 2021). While early rehabilitation has a number of benefits in the short term, including an increase in muscle strength and a reduced incidence of ICU-acquired weakness, it does not affect the long-term outcomes of PICS as measured by health questionnaires EQ-5D and SF-36 (physical functioning) (Fuke et al 2018). When patients have survived a critical illness, we need to consider not just what happens in the ICU, but what happens afterwards and across the continuum of care.

4. Surviving ICU has a significant psychological impact
It is well established that PICS affects a patient’s psychological function. Patients with PICS have been shown to have higher levels of anxiety, depression and post-traumatic stress disorder symptoms (Wade et al 2012). Relatives are also affected, with an incidence of 15–24 per cent anxiety, 4.7–36.4 per cent depression and 35–57.1 per cent post-traumatic stress disorder symptoms (van Beusekom et al 2016). In addition, one-year cognitive outcomes among ICU survivors are similar in severity to mild A
There are currently no clear guidelines on how patients with PICS should be routinely followed up. It la